Bewegung und Sport » Intensivtraining versus Ausdauertraining

[quote="Prometheus"|p4515]
Sprinters versus Long-distance Runners: How to Grow Old Healthy

Es scheint genauer gesagt um Intensivtraining vs Ausdauertraining zu gehen

http://www.spiegel.de/gesundheit/ernaehr...-a-1035938.html

Nicht nur Muskelschwäche, sondern auch Mitochondriale Entgleisungen können im Alter durch Kraftsport entgegengewirkt werden. Nicht nur im Phänotyp, sondern ganz besonders gut im Transkriptom, das dadurch fast wieder dem Muster in jüngeren Jahren entspricht.

Zitat

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Resistance Exercise Reverses Aging in Human Skeletal Muscle

Human aging is associated with skeletal muscle atrophy and functional impairment (sarcopenia). Multiple lines of evidence suggest that mitochondrial dysfunction is a major contributor to sarcopenia. We evaluated whether healthy aging was associated with a transcriptional profile reflecting mitochondrial impairment and whether resistance exercise could reverse this signature to that approximating a younger physiological age. Skeletal muscle biopsies from healthy older (N = 25) and younger (N = 26) adult men and women were compared using gene expression profiling, and a subset of these were related to measurements of muscle strength. 14 of the older adults had muscle samples taken before and after a six-month resistance exercise-training program. Before exercise training, older adults were 59% weaker than younger, but after six months of training in older adults, strength improved significantly (P<0.001) such that they were only 38% lower than young adults. As a consequence of age, we found 596 genes differentially expressed using a false discovery rate cut-off of 5%. Prior to the exercise training, the transcriptome profile showed a dramatic enrichment of genes associated with mitochondrial function with age. However, following exercise training the transcriptional signature of aging was markedly reversed back to that of younger levels for most genes that were affected by both age and exercise. We conclude that healthy older adults show evidence of mitochondrial impairment and muscle weakness, but that this can be partially reversed at the phenotypic level, and substantially reversed at the transcriptome level, following six months of resistance exercise training.

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http://journals.plos.org/plosone/article...al.pone.0000465

Hallo Scout,

was ist denn mit "im Alter" gemeint? Welche Altersgruppen hatte denn diese Studie? Beim Klick auf den Link erscheint leider "Page not found".

Das steht leider im Volltext nirgends dabei.

Ich habe übrigens den Link korrigiert.