RE: Knoblauch - 2

Kyolic aged garlic extract improves aerobic fitness in middle‑aged recreational endurance athletes: A randomized double‑blind placebo‑controlled 3 month trial
https://pmc.ncbi.nlm.nih.gov/articles/PMC11904864/

Efficacy of aged garlic extract on periodontal pockets: An 18‑month dose response study
https://pmc.ncbi.nlm.nih.gov/articles/PMC11904753/

Supplementation of aged garlic extract attenuates age-associated memory impairment and cognitive decline: Involvement of molecular pathways in the cortex and hippocampus
https://www.spandidos-publications.com/10.3892/br.2025.2075

Zitat

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Conclusion: Cholesterol-lowering activity of garlic is mediated by modulating cholesterol synthesis, absorption, and metabolism with an optimal efficacy observed after sustained use in hypercholesterolemic individuals.

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Roles of garlic and its bioactive compounds in modulating cholesterol metabolism
https://pubmed.ncbi.nlm.nih.gov/41273868/

Garlic as a functional food: a dual therapeutic strategy for cardiovascular diseases and cancer via shared molecular pathways
https://www.sciencedirect.com/science/ar...756464626000022

Garlic and Its Bioactive Derivatives as Host-Directed Therapies in Sepsis
https://www.dovepress.com/garlic-and-its...ext-article-NDS

Zitat

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Garlic-derived metabolite S1PC promotes eNAMPT-EV secretion from adipose tissue
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S1PC activates LKB1 by enhancing its tertiary complex formation with STRAD and MO25
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S1PC improves age-related muscle function via hypothalamic signaling in aged mice
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S1PC increases circulating eNAMPT levels in middle-aged humans with healthy fat mass

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Garlic-derived metabolite activates LKB1, promotes adipose eNAMPT secretion, and improves age-related muscle function via hypothalamic signaling
https://www.sciencedirect.com/science/ar...Exv5QTXNzfiSzEQ