Jetzt beginnt wieder die Aussat für Sommerportulak. Portulaca oleracea L.: a review of phytochemistry and pharmacological effects. http://www.ncbi.nlm.nih.gov/pubmed/25692148
Ich hab heuer auch zum ersten mal Portulak angepflanzt.
Schmeckt gut und wächst echt wie verrückt, ist eindeutig die schnellwachsenste Pflanze meines AA/LEF-Gartens
Aber Speedy, achtest du eigentlich darauf, dass die Pflanzen ale einen Abstand von 10cm haben?
Ich habe 2 große Töpfe, in denen sie derzeit teilweise sehr dicht zusammen stehen. Ein paar habe ich als sie noch ganz klein waren in andere Töpfe gepflanzt bei der ersten Ernte ein paar ganze Pflanzen rausgerissen.
Bringen sie weniger Ertrag, wenn sie dichter stehen, oder ist es egal?
Zitat von La_Croix im Beitrag #2 Aber Speedy, achtest du eigentlich darauf, dass die Pflanzen ale einen Abstand von 10cm haben?
Ich habe 2 große Töpfe, in denen sie derzeit teilweise sehr dicht zusammen stehen. Ein paar habe ich als sie noch ganz klein waren in andere Töpfe gepflanzt bei der ersten Ernte ein paar ganze Pflanzen rausgerissen.
Bringen sie weniger Ertrag, wenn sie dichter stehen, oder ist es egal?
also ich habe einen großen Garten und reichlich Platz für den Anbau von Gemüse, sodass ich die entsprechenden Abstände in der Regel schon beachte. Allerdings sehe ich gerade bei Portulak kein Problem, wenn die Pflanzen ein wenig dichter zusammenstehen.
In den letzten Tagen haben alle zu blühen begonnen. Leider schmecken die Blätter, sobald die ersten Blüten da sind, echt nicht mehr gut. Man kann damit weder kochen, noch Salat machen.
Pflanzt du öfters Portulak an (z.B im Abstand von 2 - 3 Wochen), damit die Pflanzen zu unterschiedlichen Zeiten in die Blüte kommen, damit an die länger nutzen kann?
Pflanzt du öfters Portulak an (z.B im Abstand von 2 - 3 Wochen), damit die Pflanzen zu unterschiedlichen Zeiten in die Blüte kommen, damit an die länger nutzen kann?
Hier mal ein paar sehr interessante Studienergebnisse zu Portulak!
Portulaca oleracea extracts protect human keratinocytes and fibroblasts from UV-induced apoptosis. Portulaca oleracea extracts, known as Ma Chi Hyun in the traditional Korean medicine, show a variety of biomedical efficacies including those in anti-inflammation and anti-allergy. In this study, we investigate the protective activity of the P. oleracea extracts against UVB-induced damage in human epithelial keratinocytes and fibroblasts by several apoptosis-related tests. The results suggest that P. oleracea extracts have protective effects from UVB-induced apoptosis. http://www.ncbi.nlm.nih.gov/pubmed/25234830
Anti-TNF-α activity of Portulaca oleracea in vascular endothelial cells. Vascular inflammation plays a key role in the pathogenesis and progression of atherosclerosis, a main complication of diabetes. The present study investigated whether an aqueous extract of Portulaca oleracea (AP) prevents the TNF-α-induced vascular inflammatory process in the human umbilical vein endothelial cell (HUVEC). The stimulation of TNF-α induced overexpression of adhesion molecules affects vascular cell adhesion molecule (VCAM)-1, intercellular adhesion molecule (ICAM)-1 and E-selectin for example. However, AP significantly suppressed TNF-α-induced over-expression of these adhesion molecules in a dose-dependent manner. In addition, pretreatment with AP dose-dependently reduced an increase of the adhesion of HL-60 cells to TNF-α-induced HUVEC. Furthermore, we observed that stimulation of TNF-α significantly increased intracellular reactive oxygen species (ROS) production. However, pretreatment with AP markedly blocked TNF-α-induced ROS production in a dose-dependent manner. The western blot and immunofluorescence analysis showed that AP inhibited the translocation of p65 NF-κB to the nucleus. In addition, AP suppressed the TNF-α-induced degradation of IκB-α and attenuated the TNF-α-induced NF-κB binding. AP also effectively reduced TNF-α-induced mRNA expressions of monocyte chemoattractant protein (MCP)-1 and interleukin (IL)-8 in a dose-dependent manner. Taken together, AP prevents the vascular inflammatory process through the inhibition of intracellular ROS production and NF-κB activation as well as the reduction of adhesion molecule expression in TNF-α-induced HUVEC. These results suggested that AP might have a potential therapeutic effect by inhibiting the vascular inflammation process in vascular diseases such as atherosclerosis. http://www.ncbi.nlm.nih.gov/pubmed/22754320
The anti-inflammation and pharmacokinetics of a novel alkaloid from Portulaca oleracea L. OBJECTIVES: This study was to elucidate the pharmacokinetics of a novel alkaloid, 6-acetyl-2,2,5-trimethyl-2,3-dihydrocyclohepta[b ]pyrrol-8(1H)-one, named oleracone isolated from Portulaca oleracea L., and to examine the anti-inflammatory ability with lipopolysaccharide (LPS) stimulated macrophages. KEY FINDINGS: Oleracone was a novel alkaloid first isolated from Portulaca oleracea L. and possessed unique structure in natural products, whose anti-inflammatory effecting on nitrite oxide production and several pivotal pro-inflammatory cytokines was found at the concentration of 50 μm, and the pharmacokinetic results indicated that oleracone was rapidly distributed with Tmax of 15.7 min after oral administration and presented a higher oral absolute bioavailability to be 74.91 ± 10.7%. CONCLUSIONS: Oleracone as novel alkaloid presented remarkably anti-inflammatory effect, which was rapid distributed in rat with high bioavailability of 74.91 ± 10.7%. http://www.ncbi.nlm.nih.gov/pubmed/26888212
Purslane suppresses osteoclast differentiation and bone resorbing activity via inhibition of Akt/GSK3β-c-Fos-NFATc1 signaling in vitro and prevents lipopolysaccharide-induced bone loss in vivo. Purslane (Portulaca oleracea L.) is popular as a potherb in many areas of Europe, Asia, and the Mediterranean region and is widely distributed around the globe. It has a wide range of pharmacological effects, such as antibacterial, anti-aging, anti-inflammatory, and anti-oxidative properties. Although the extract of purslane has numerous beneficial pharmacological effects, its effect on osteoclasts remains unknown. We aimed to investigate the anti-osteoclastogenic activity in vitro and in vivo and to elucidate the underlying mechanism. The effect of purslane on the differentiation and function of bone marrow-derived macrophages (BMMs) into osteoclasts was examined using a phenotype assay such as tartrate-resistant acid phosphatase (TRAP) staining, F-actin staining, and pit assay and followed by confirmation by real-time reverse transcription polymerase chain reaction (RT-PCR) and Western blot analysis. To address the effect of purslane in vivo, the inflammatory, lipopolysaccharide (LPS)-induced osteolysis mouse model was chosen. Bone volume and bone microarchitecture were evaluated by microcomputed tomography and histologic analysis. Purslane inhibited receptor activator of nuclear factor-kappa B ligand (RANKL)-stimulated osteoclast differentiation accompanied by inhibition of Akt/glycogen synthase kinase 3β (GSK3β) signaling, which could underlie purslane-induced downregulation of c-Fos and nuclear factor of activated T cells 1 (NFATc1) expression levels, transcription factors that regulate osteoclast-specific genes, as well as osteoclast fusion and resorption-related molecules. Moreover, in vivo studies further verified the bone protection activity of purslane in the LPS-induced osteolysis animal model. Purslane could exhibit its anti-osteoclastogenic activity by inhibiting Akt/GSK3β-c-Fos-NFATc1 signaling cascades. Therefore, purslane is a potential natural medicine for the treatment of osteoclast-related diseases. http://www.ncbi.nlm.nih.gov/pubmed/25744460
Effects of Portulaca oleracea ethanolic extract on reproductive system of aging female mice. BACKGROUND: Aging contains morphological and functional deterioration in biological systems. D-galactose (D-gal) generates free radicals and accelerates aging. Portulaca oleracea (Purslane) may have protective effect against oxidative stress. RESULTS:In D-gal treated and aging animals, LH and FSH levels were significantly increased (p<0.001) while estrogen and progesterone levels were significantly reduced (p<0.001) in comparison with control group. MDA contents were significantly increased in ovaries and uterus of D-gal and aging groups (p<0.01). Superoxide dismutase (SOD) (p<0.001) and catalase (p<0.01) activities were significantly decreased in both aging and D-gal treated animals. Ovarian follicles were degenerated and atrophy on uterine wall and endometrial glands was observed in D-gal and aging groups. Alteration in hormone levels, MDA contents and antioxidant activity were significantly reversed by Purslane (p<0.05). Purslane could also improve histological changes such as atrophy of endometrium. CONCLUSION: These findings indicate that Purslane can attenuate aging alternations induced by D-gal and aging in female reproductive system. http://www.ncbi.nlm.nih.gov/pubmed/27294220
Protective effects of ethanol extract from Portulaca oleracea L on dextran sulphate sodium-induced mice ulcerative colitis involving anti-inflammatory and antioxidant. Portulaca oleracea L., (POL) is one of commonly used medicine-food herbs and has a cosmopolitan distribution in many countries. Many studies showed that POL exhibited a wide range of pharmacological effects such as anti-inflammatory and liver complaints. In the clinical studies, POL was usually used for the treatment of UC disease and the clinical efficacy was well, but the mechanism and scientific intension was still unknown. In the present study, we studied the protective effects of the ethanol extract from POL on dextran sulphate sodium-induced UC in C57BL/6 mice model through oxidative stress and inflammatory pathway. The results demonstrated that the ethanol extract from POL could exhibit the effective protection for the DSS induced UC by increasing the colon length, decreasing body weight loss and the disease activity index score, inhibiting oxidative stress response through the MDA, NO, SOD activities, reducing the mRNA expressions of pro-inflammatory cytokines (TNF-α, IL-1β and IL-6) and the protein expressions of TNF-α and NF-kB p65. These results may prove that POL could be considered as a useful and effective botanical compound from the edible plant to be used in UC through the oxidative stress and inflammatory activities. http://www.ncbi.nlm.nih.gov/pubmed/27347321
The Aqueous Extract of Portulaca Oleracea Ameliorates Neurobehavioral Dysfunction and Hyperglycemia Related to Streptozotocin-Diabetes Induced in Ovariectomized Rats. http://www.ncbi.nlm.nih.gov/pubmed/27642327
Portulaca Oleracea L. (Purslane) Extract Protects Endothelial Function by Reducing Endoplasmic Reticulum Stress and Oxidative Stress through AMPK Activation in Diabetic Obese Mice https://pubmed.ncbi.nlm.nih.gov/38136251/
Network Pharmacology Combined with Experimental Validation to Investigate the Mechanism of the Anti-Hyperuricemia Action of Portulaca oleracea Extract https://www.mdpi.com/2072-6643/16/20/3549