Heilung, Prävention und Verjüngung durch Ernährung » Hibiskus

Hallo,

Hibiskusblüten, werden den meisten Früchtetees, die man bei uns im Supermarkt kaufen kann zugesetzt und damit wird der Gesundheit der meisten Menschen ein großer Dienst erwiesen.

Hibiskustee hat wohl einen der höchsten gehalte an Antioxidantien, unter den Getränken.

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Hibiscus sabdariffa wird, wie auch andere Malven, häufig Hagebuttentee und anderen Früchtetees zugesetzt. Ein beliebtes Getränk ist Hibiskusblütentee nicht nur in Ägypten und im Sudan als Karkadeh (كركديه), sondern auch in Mexiko (Agua de Jamaica). Der tiefrote Tee wird heiß oder kalt getrunken. In der vegetarischen Küche Südasiens (z. B. in Sri Lanka) findet die Hibiscusblüte auch Verwendung in Currygerichten.[3]

Auch pharmazeutisch werden die Hibiskusblüten eingesetzt. Verwendet werden die zur Fruchtzeit geernteten, getrockneten Kelche und Außenkelche von Hibiscus sabdariffa. Die darin enthaltenen Säuren wie z. B. Zitronensäure, Apfelsäure, Weinsäure und Hibiskussäure (Allohydroxyzitronensäurelacton) ergeben den säuerlichen Geschmack. Die enthaltenen Anthocyane wie z. B. Delphinidin und Cyanidin färben den Teeaufguss dunkelrot. In erster Linie werden sie daher als Korrigens für Geschmack und Aussehen eingesetzt. Indikationen wie Erkältungen, Kreislaufbeschwerden, Ekzeme, mildes Laxans sowie Appetitanregung sind nicht belegt, aber in der Volksmedizin weit verbreitet. Hibiskus verfügt ebenfalls über eine hohe Konzentration an Vitamin C und in Fernost sagt man ihm eine blutdrucksenkende Wirkung nach. Auch in der afrikanischen Volksmedizin wird Hibiskus als Tee eingesetzt.

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https://de.wikipedia.org/wiki/Hibiskus#Verwendung

Was den Nierenschutz angeht, schneidet Hibiscustee, genau so gut ab, wie Grüner Tee.
https://www.hindawi.com/journals/aps/2014/389834/

Auch Immunmodulierend, scheint Hibiskus zu wirken. Zumindest eine Injektion mit Hibiskustee, hat bei einer Mausstudie ein ansteigen der Antikörperkonzentration von 38% bewirkt. Den Tee oral zu konsumieren, wird zwar vermutlich weniger Effekt haben, aber wohl in die Selbe Richtung gehen.
https://www.ncbi.nlm.nih.gov/pubmed/24175424

Hibiskus gegen Diabetes?
Hibiscus rosa sinensis Linn. Petals Modulates Glycogen Metabolism and Glucose Homeostasis Signalling Pathway in Streptozotocin-Induced Experimental Diabetes.

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The objective of the present study was to evaluate the effect of ethyl acetate fraction of Hibiscus rosa sinensis Linn. petals on experimental diabetes at a dose of 25 mg/kg body weight and it was compared with standard anti-diabetic drug metformin. The elevated levels of serum glucose (398.56 ± 35.78) and glycated haemoglobin (12.89 ± 1.89) in diabetic rats were significantly decreased (156.89 ± 14.45 and 6.12 ± 0.49, respectively) by Hibiscus rosa sinensis petals (EHRS) administration. Hepatotoxicity marker enzyme levels in serum were normalized. The fraction supplementation restored the glycogen content by regulating the activities of glycogen metabolizing enzymes. It significantly modulated the expressions of marker genes involved in glucose homeostasis signalling pathway. Histopathological analysis of liver and pancreas supported our findings. The overall effect was comparable with metformin. Hence, our study reveals the role of hibiscus petals for alleviation of diabetes complications, thus it can be propagated as a nutraceutical agent.

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https://www.ncbi.nlm.nih.gov/pubmed/26590603


Auch gegen Krebs, scheint Hibiskus ein gewisses Potential zu habe.
Zur Vorbeugung etwa:
Effect of Hibiscus rosa sinensis extract on hyperproliferation and oxidative damage caused by benzoyl peroxide and ultraviolet radiations in mouse skin.
https://www.ncbi.nlm.nih.gov/pubmed/15546476


Aber auch verschiedene bereits entstandene Krebszellen, kann man mit Hibiskus angreifen:
Components in aqueous Hibiscus rosa-sinensis flower extract inhibit in vitro melanoma cell growth.
https://www.ncbi.nlm.nih.gov/pubmed/28053887

Antitumoral Effect of Hibiscus sabdariffa on Human Squamous Cell Carcinoma and Multiple Myeloma Cells.
https://www.ncbi.nlm.nih.gov/pubmed/27618152

Traditional preparations of kava (Piper methysticum) inhibit the growth of human colon cancer cells in vitro.
https://www.ncbi.nlm.nih.gov/pubmed/28160848

Hibiscus sabdariffa leaf polyphenolic extract induces human melanoma cell death, apoptosis, and autophagy.
https://www.ncbi.nlm.nih.gov/pubmed/25694272

Antimicrobial, antiparasitic and anticancer properties of Hibiscus sabdariffa (L.) and its phytochemicals: in vitro and in vivo studies.
https://www.ncbi.nlm.nih.gov/pubmed/27118499






Hibiscus sabdariffa L. – A phytochemical and pharmacological review

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Highlights

• H. sabdariffa has a wide range of traditional and potential new health food uses.
• The evidence is largely based on in vitro and in vivo studies of varying quality.
• A better chemical profiling of the extracts studied pharmacologically is essential.
• Further research with Hibiscus species on possible gynaecologic uses is warranted.
• Hs preparations, esp. Hs tea and aqueous extracts are safe for use in foods.

Abstract

Hibiscus sabdariffa L. (Hs, roselle; Malvaceae) has been used traditionally as a food, in herbal drinks, in hot and cold beverages, as a flavouring agent in the food industry and as a herbal medicine. In vitro and in vivo studies as well as some clinical trials provide some evidence mostly for phytochemically poorly characterised Hs extracts. Extracts showed antibacterial, anti-oxidant, nephro- and hepato-protective, renal/diuretic effect, effects on lipid metabolism (anti-cholesterol), anti-diabetic and anti-hypertensive effects among others. This might be linked to strong antioxidant activities, inhibition of α-glucosidase and α-amylase, inhibition of angiotensin-converting enzymes (ACE), and direct vaso-relaxant effect or calcium channel modulation. Phenolic acids (esp. protocatechuic acid), organic acid (hydroxycitric acid and hibiscus acid) and anthocyanins (delphinidin-3-sambubioside and cyanidin-3-sambubioside) are likely to contribute to the reported effects.

More well designed controlled clinical trials are needed which use phytochemically characterised preparations. Hs has an excellent safety and tolerability record.

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http://www.sciencedirect.com/science/art...30881461400692X

Hibiskus gegen Bluthochdruck?



Could Hibiscus Tea be Better than High Blood Pressure Drugs?

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When it comes to high blood pressure, a completely preventable condition, there are many natural solutions. Things like cayenne pepper, apple cider vinegar, and celery are just a few alternatives, along with broad dietary and lifestyle changes. But many people aren’t aware of the blood pressure lowering benefits of hibiscus.

It’s believed these benefits are related to the high concentration of anthocyanins, which work to inhibit angiotensin-converting enzyme (ACE). A study published in the Journal of Enthopharmacology affirmed this in looking at folk medicine applications of hibiscus in Mexico.

In 2008, Dr. Diane McKay presented her own research on hibiscus to the annual conference of the American Heart Association. Dr. McKay, of Tufts University, conducted a study on 65 people between the ages of 30 and 70 who had been diagnosed with prehypertension or mild hypertension.

After receiving hibiscus tea daily for six weeks, participants experienced reduced diastolic, systolic, and mean arterial pressures when compared with those who received a placebo. The effects were most pronounced in those with the highest beginning baseline blood pressures.

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http://naturalsociety.com/hibiscus-bette...pressure-drugs/


Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials.

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RESULTS: Fixed-effect meta-regression indicated a significant effect of H. sabdariffa supplementation in lowering both SBP (weighed mean difference -7.58 mmHg, 95% confidence interval -9.69 to -5.46, P < 0.00001) and DBP (weighed mean difference -3.53 mmHg, 95% confidence interval -5.16 to -1.89, P < 0.0001). These effects were inversely associated with baseline BP values, and were robust in sensitivity analyses.
CONCLUSION: This meta-analysis of RCTs showed a significant effect of H. sabdariffa in lowering both SBP and DBP. Further well designed trials are necessary to validate these results.

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https://www.ncbi.nlm.nih.gov/pubmed/25875025


Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: A comprehensive review of animal and human studies
http://www.sciencedirect.com/science/art...367326X13000063

Hmm... hmmm..

hoch in Aluminium und Mangan?

Antioxidant and antibacterial activities of hibiscus (Hibiscus rosa-sinensis L.) and Cassia (Senna bicapsularis L.) flower extracts

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In conclusion, results of this study showed hibiscus and Cassia flowers to encompass significant amount of antioxidant compounds, with the extracts exhibiting rich antioxidant activities. In addition, both the flower extracts also possessed antibacterial activity against various Gram-positive and Gram-negative food-borne bacterial pathogens. Results on antioxidants and antibacterial activity indicate the prospective of utilizing hibiscus and Cassia flower extracts as a mode of natural food preservative. Results on color analysis highlight the potential of utilizing these flowers as a natural food colorant. With regard to functional group of compounds, both the flowers showed the presence of polysaccharides, suberin and lipids/triglycerides. All the findings of the present study warrant further research wherein hibiscus and Cassia flowers need to be explored commercially as a low-cost, natural preservative during the preparation of novel functional foods or in nutraceutical applications.

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http://www.sciencedirect.com/science/art...018364712000638

Antimutagenic Effect of Hibiscus sabdariffa L. Aqueous Extract on Rats Treated with Monosodium Glutamate.
Hibiscus sabdariffa L. is a plant of the Malvaceae family, commonly known as roselle. H. sabdariffa is known to contain antioxidant, cholesterol-lowering, antiobesity, insulin resistance reduction, antihypertensive, and skin cancer chemopreventive properties. This study evaluated the effects of H. sabdariffa aqueous extract against cyclophosphamide (CPA, 25 mg/Kg) induced damage to DNA in male Wistar rats by micronucleus test. Samples of H. sabdariffa calyx were obtained in the municipality of Barra do Garças, Mato Grosso, Brazil. The aqueous extract was prepared by infusion and each animal received a daily dose of 400 mg/Kg by gavage for 15 consecutive days of treatment. The presence of anthocyanins was confirmed by ferric chloride test and phenolic compounds using high-performance liquid chromatography, with emphasis on the identification of rutin. The animals were sacrificed by deepening of anaesthesia to obtain bone marrow and determination of the frequency of micronucleated polychromatic erythrocytes. The group treated with the aqueous extract of H. sabdariffa revealed a 91% reduction in micronucleus frequency when compared with the positive control group. Under the conditions tested, H. sabdariffa L. presented a protective effect to CPA-induced damage to DNA of the treated animals, and it is a potential candidate as a chemopreventive agent against carcinogenesis.

https://www.ncbi.nlm.nih.gov/pubmed/28197528



Gegen Hypercholesterinämie, scheint Hibiskus auch zu helfen. Hibiskus scheint die gesamte Lipogenese in der Leber zu reduzieren! Es ist ein weiteres Multitalent für die Gesundheit.

Hibiskus senkt Cholesterin
Hibiskus scheint gegen Cholesterin zu wirken. Forscher haben nachgewiesen, dass in der Blüte der tropischen Pflanze Antioxidantien vorhanden sind, die gefährliche Fettabbauprodukte in den Arterien reduzieren können.

Ein Extrakt der Hibiskus-Blume könnte nach Ansicht von taiwanesischen Forschern dieselbe positive Wirkung auf den Organismus haben, wie der Genuss von Tee und Wein. Einem Wissenschaftlerteam der Medical University in Taiwan ist es gelungen, nachzuweisen, dass der Pflanzenwirkstoff bei Tieren Cholesterin verringern kann. Daraus lässt sich nach Ansicht der Forscher schließen, dass dies auch beim Menschen möglich sein muss.

Hibiscus sabdariffa, eine ursprünglich in China, Indien und Taiwan beheimatete Pflanze, ist in der traditionellen asiatischen Medizin als Medikament gegen Bluthochdruck und Leberstörungen bekannt. Die Forscher haben nachgewiesen, dass in der Pflanze Antioxidantien vorhanden sind, die gefährliche Fettabbauprodukte in den Arterien reduzieren können. Bei Ratten konnte der Pflanzenextrakt jedenfalls LDL-Cholesterin deutlich reduzieren. Forschungsleiter Chau-Jong Wang berichtet, dass es das erste mal sei, dass solche Wirkungen von Hibiskus nachgewiesen werden konnten.

http://www.medizinauskunft.de/artikel/di...09_hibiskus.php



The hypolipidemic effect of Hibiscus sabdariffa polyphenols via inhibiting lipogenesis and promoting hepatic lipid clearance.
Hibiscus sabdariffa extract (HSE) was shown to lower the plasma lipid level and reduce the liver damage. In the present study, we investigated if Hibiscus sabdariffa polyphenols (HPE) exerted a hypolipidemic effect and its putative mechanism on liver. HPE exhibited more potency to decrease plasma cholesterol and LDL cholesterol than the crude extract HSE, and increased HDL cholesterol dose-dependently. It decreased the lipid content of hepatocyte through the activation of AMPK and reduction of SREBP-1, thus inhibiting the expression of fatty acid synthase and HMG-CoA reductase. LDLR and LDL binding of HepG2 cells were enhanced when treated with HPE. In conclusion, HPE is worthy of being further investigated and could be developed as an adjunctive for hepatic lipid control and hypolipidemic therapy.

https://www.ncbi.nlm.nih.gov/pubmed/20017484




Hibiscus sabdariffa extract inhibits the development of atherosclerosis in cholesterol-fed rabbits.
Hibiscus sabdariffa L., a local soft drink material and medicinal herb, is usually used effectively in native medicines against hypertension, pyrexia, and liver disorders. Here, we report an extract, HSE (H. sabdariffa extract), which is designed to exhibit hypolipidemia and antiatherosclerotic effects in rabbits with experimental atherosclerosis. New Zealand White rabbits were fed with a normal diet, high cholesterol (1.3%), lard oil (3%) diet (HCD) with or without 0.5 or 1% HSE for 10 weeks. The levels of triglyceride, cholesterol, and low-density lipoprotein cholesterol (LDL-C) were lower in the serum of rabbits fed HCD plus HSE than in the serum of rabbits fed HCD. Feeding HSE (0.5 and 1% in the diet) to rabbits significantly reduced severe atherosclerosis in the aorta. Histopathological examination showed that HSE reduced foam cell formation and inhibited smooth muscle cell migration and calcification in the blood vessel of rabbits. These results suggest that HSE inhibits serum lipids and shows an antiatherosclerotic activity.

https://www.ncbi.nlm.nih.gov/pubmed/12926900




Polyphenolic extract from Hibiscus sabdariffa reduces body fat by inhibiting hepatic lipogenesis and preadipocyte adipogenesis.
Diets high in fat lead to excess lipid accumulation in adipose tissue, which is a crucial factor in the development of obesity, hepatitis, and hyperlipidemia. In this study, we investigated the anti-obesity effect of Hibiscus sabdariffa extract (HSE) in vivo. Hamsters fed a high-fat diet (HFD) develop symptoms of obesity, which were determined based on body weight changes and changes in plasma and serum triglycerides, free fatty acid concentrations, total cholesterol levels, LDL-C levels, HDL-C levels, and adipocyte tissue weight. HFD-fed hamsters were used to investigate the effects of HSE on symptoms of obesity such as adipogenesis and fatty liver, loss of blood glucose regulation, and serum ion imbalance. Interestingly, HSE treatment effectively reduced the effects of the HFD in hamsters in a dose-dependent manner. Further, after inducing maturation of preadipocytes, Hibiscus sabdariffa polyphenolic extract (HPE) was shown to suppress the adipogenesis of adipocytes. However, HPE does not affect the viability of preadipocytes. Therefore, both HSE and HPE are effective and viable treatment strategies for preventing the development and treating the symptoms of obesity.

https://www.ncbi.nlm.nih.gov/pubmed/26489044

Nach Matcha und Grüntee
Senkt Blutdruck und Cholesterin: Deshalb gilt Hibiskustee als neues Wundermittel
Es ist nur eine Frage der Zeit, bis sich nach Grüntee und Matcha ein neuer Teetrend durchsetzt: Viele Argumente sprechen dafür, dass Hibiskus das Rennen macht. Wir zeigen, was er tatsächlich kann und worauf man beim Trinken achten sollten.
https://www.focus.de/gesundheit/gesund-l...id_9983051.html

Efficacy and safety of Hibiscus sabdariffa in cardiometabolic health: An overview of reviews and updated dose-response meta-analysis
https://www.sciencedirect.com/science/ar...010X?via%3Dihub