RE: Granatapfelsaft - 4

Urolithin A alleviates schizophrenic-like behaviors and cognitive impairment in rats through modulation of neuroinflammation, neurogenesis, and synaptic plasticity
https://www.nature.com/articles/s41598-025-93554-9

Neuroprotective, Antioxidant and Anti-Inflammatory Effect of Greek Pomegranate Seed Oil on N2a Neuroblastoma Cells and Mild Cognitive Impairment Patients
https://www.mdpi.com/2079-7737/14/5/548

The Significant Antioxidant Effect Exerted by Pomegranate (Punica granatum): The Hidden Polyphenols
https://www.mdpi.com/2076-3921/15/3/276

Pomegranate (Punica granatum L.) and Disease-Related Enzyme Modulation
https://www.mdpi.com/3042-9250/1/1/3

Anti-Atherogenic Actions of Pomegranate Polyphenol Punicalagin and Its Metabolites: In Vitro Effects on Vascular Cells and In Vivo Atheroprotection by Urolithin A via Anti-Inflammatory and Plaque-Stabilising Mechanisms
https://www.mdpi.com/2076-3921/15/4/507?...HEQYenkFDwZW5EA

Zitat

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UroA can restore the damaged autophagic lysosomal system during AD progression.
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UroA broadly suppresses neuroinflammation in the AD process.
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The ameliorative effect of UroA on AD depends on the reprogramming of the dysregulated AMPK/SIRT/mTOR axis.
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Combining therapies with nanoparticle delivery enhances UroA’s bioavailability and bioactivity.

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Urolithin A: Potential to enhance autophagic clearance and mitigate neuroinflammation in Alzheimer’s disease
https://www.sciencedirect.com/science/ar...1492?via%3Dihub

Urolithin A activates aryl hydrocarbon receptor-NLRP6-mediated pathways in intestinal epithelial cells to modulate mucosal immunity and strengthen gut barrier integrity
https://www.nature.com/articles/s41467-0...sSUU_TjTUSQpGlg

Compound produced after eating pomegranates targets stiff-heart failure pathway, early tests suggest
https://medicalxpress.com/news/2026-08-c...ILd7zmprVR2FD9A