RE: Mitochondrien - 19

Loss of PGC-1α causes depot-specific alterations in mitochondrial capacity, ROS handling and adaptive responses to metabolic stress in white adipose tissue
https://www.sciencedirect.com/science/ar...567724925000315

Mitochondria transplantation transiently rescues cerebellar neurodegeneration improving mitochondrial function and reducing mitophagy in mice
https://www.nature.com/articles/s41467-025-58189-4

Mitochondrial Dysfunction in Endothelial Cells: A Key Driver of Organ Disorders and Aging
https://www.mdpi.com/2076-3921/14/4/372

Hallo Speedy,

bei den Kapillaren hilft u.a. die Ozontherapie, damit die Zellen wieder mit genügend Sauerstoff sowie Nährstoffen versorgt werden können.

VG

Roger

Mitochondrial function: A new direction for the targeted treatment of cardiovascular diseases with Chinese herbal medicine
https://www.sciencedirect.com/science/ar...0093?via%3Dihub

Mitochondria at the Crossroads: Linking the Mediterranean Diet to Metabolic Health and Non-Pharmacological Approaches to NAFLD
https://www.mdpi.com/2072-6643/17/7/1214

Uni Jena: Dieses Protein hält Mitochondrien gesund und beeinflusst damit das Altern
https://www.mdr.de/wissen/medizin-gesund...in-atr-100.html

Aging-associated mitochondrial decline accelerates skin aging and obesity
https://www.sciencedirect.com/science/ar...022202X25003951

Finde die Effekte hier schon beeindruckend bei der Maus. Beim Menschen wird es ohne beispielsweise einer liposomalen Formulierung allerdings eher nicht funktionieren. Zeigt dennoch mal wieder wozu natürliche Substanzen in der Lage sein können.

Kaempferol enhances ER-mitochondria coupling and protects motor neurons from mitochondrial dysfunction and ER stress in C9ORF72-ALS
https://actaneurocomms.biomedcentral.com...478-025-01927-y

Hallo Speedy,

bei ca. 15 Prozent der ALS Patienten konnte bisher eine genetische Veranlagung nachgewiesen werden. Aktuell hat u.a. die antientzündliche Behandlung die größten Chance auf eine Besserung der ALS Beschwerden: https://ganzemedizin.at/nadir-protokoll-...ateralsklerose/ .

VG

Roger

Involvement of Oxidative Stress in Mitochondrial Abnormalities During the Development of Heart Disease
https://www.preprints.org/manuscript/202504.0012/v1


Älteres aber wie ich finde sehr interessantes Paper was man mal gelesen haben sollte:

Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity
https://www.frontiersin.org/journals/cel...2020.00051/full

VDAC1-Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid-β Oligomers Toxicity in Alzheimer's Disease
https://onlinelibrary.wiley.com/doi/10.1111/acel.70069

Calcium acts as a critical determinant of mitochondria-nuclear networking driven retrograde signaling
https://www.sciencedirect.com/science/ar...0260?via%3Dihub

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis
https://www.cell.com/molecular-cell/full...2765(25)00196-0

Mitochondrial Imbalance in Down Syndrome: A Driver of Accelerated Brain Aging?
https://www.aginganddisease.org/EN/10.14336/AD.2025.0189

Synapses drive local mitochondrial ATP synthesis to fuel plasticity
https://www.biorxiv.org/content/10.1101/...9.648032v1.full

Mitochondria-targeted rosmarinic acid: Its role against oxidative damage
https://www.sciencedirect.com/science/ar...753332225003087

Targeting the Electron Transport System for Enhanced Longevity
https://www.mdpi.com/2218-273X/15/5/614

Mitochondrial connection to Alzheimer's disease and heart failure
https://www.sciencedirect.com/science/ar...468867325000185

Role of Mitochondrial Dysfunction in UV-Induced Photoaging and Skin Cancers
https://onlinelibrary.wiley.com/doi/10.1111/exd.70114

Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males
https://www.sciencedirect.com/science/ar...666379125001892

Targeting Mitochondria in Bone and Cartilage Diseases: A Narrative Review
https://www.sciencedirect.com/science/ar...213231725001806