RE: Long Covid - 22

Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest
https://www.medrxiv.org/content/10.1101/...5.02.25326885v1

What exactly is brain fog? Here’s what scientists are finding out.
https://www.nationalgeographic.com/healt...rain-fog-causes

Palmitoylated COX-2Cys555 reprogramed mitochondrial metabolism in pyroptotic inflammatory injury in patients with post-acute COVID-19 syndrome
https://www.sciencedirect.com/science/ar...090123225002991

Age-associated changes in the heart: implications for COVID-19 therapies
https://www.aging-us.com/article/206251/...ez43vRrocT28Dyg

Association between COVID-19 and the development of chronic kidney disease in patients without initial acute kidney injury

https://www.nature.com/articles/s41598-025-96032-4

Zitat

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COVID-19 patients showed higher 12-month risks of advanced CKD (hazard ratio [HR]:2.02, 95% confidence interval [CI]:1.69–2.42, p < 0.0001), AKI (HR 3.04, 95%CI:2.61–3.55, p < 0.0001), and estimated glomerular filtration rate < 60 mL/min/1.73 m2 (HR:3.01, 95%CI:2.74–3.30, p < 0.0001) compared to influenza patients.

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Kommentar: Das reiht sich nahtlos in die Fülle der Studien ein, die zeigen, dass eine SARS-CoV-2-Infektion Organe langfristig schädigen kann, besonders die mit niedriger Regenerationskapazität (Nieren, Gehirn).

SARS-CoV-2 damages cardiomyocyte mitochondria and implicates long COVID-associated cardiovascular manifestations
https://www.sciencedirect.com/science/ar...090123225003066

Spermidin Infusionen wären meiner Ansicht nach hier ein möglicher Therapie Ansatz. Infusionen da die orale Route hier vermutlich nur sehr geringe Effekte zeigen dürfte.

Gastrointestinal Barrier Disruption in Post-COVID Syndrome Fatigue Patients
https://onlinelibrary.wiley.com/doi/10.1111/all.16593

Adenosine deaminase mediates endothelial inflammation via an ADA1-CD26 interaction in post-COVID
https://www.frontiersin.org/journals/pha...25.1578973/full

Low-Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients
https://www.frontiersin.org/journals/mol...25.1582967/full

Elevated adipokines and myokines are associated with fatigue in long COVID patients
https://www.frontiersin.org/journals/med...25.1547886/full

Myostatin und Irisin. Dann dürfte theoretisch von Sulforaphan, Kreatin oder dem Peptid MOTS- c profitiert werden. Pinealon soll regulierend auf Irisin wirken.

COVID virus 'reprograms' infection fighters into immune system suppressors, study shows
https://medicalxpress.com/news/2025-05-c...qdnMUVsxqO2-0oQ

Intravenous SARS-CoV-2 Spike protein induces neuroinflammation and alpha-synuclein accumulation in brain regions relevant to Parkinson’s disease
https://www.sciencedirect.com/science/ar...889159125001977

Zitat von Speedy im Beitrag #534

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COVID virus 'reprograms' infection fighters into immune system suppressors, study showshttps://medicalxpress.com/news/2025...qdnMUVsxqO2-0oQ

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Targeting the epipharynx to disrupt the residual triggers of COVID-19 in patients with long COVID
https://medicalxpress.com/news/2025-05-e...eZOwpCC0a4cuqOw

Exercise-induced Changes in Microclotting and Cytokine Levels Point to Vascular Injury and Inflammation in People with Long COVID
https://www.researchsquare.com/article/rs-6717727/v1

A Proposed Mechanism for ME/CFS Invoking Macrophage FcγRI and Interferon Gamma
https://www.qeios.com/read/8GI3CT

Exploring the role of mitochondrial dysfunction and aging in COVID-19-Related neurological complications
https://link.springer.com/article/10.1007/s11033-025-10586-0

Post-COVID pulmonary sequelae: Mechanisms and potential targets to reduce persistent fibrosis
https://www.sciencedirect.com/science/ar...163725825001032

NAC wird häufig in einem Long Covid Regime eingesetzt. Viele beachten aber nicht, dass Bromelain unbedingt dazu gehört.

The Combination of Bromelain and Acetylcysteine (BromAc) Synergistically Inactivates SARS-CoV-2
https://pmc.ncbi.nlm.nih.gov/articles/PM...QLRTGivw5e3kzDQ

GABA and GABAergic dysfunction in COVID-19: Piecing the puzzle with targeting immunity and several inflammatory pathways
https://www.sciencedirect.com/science/ar...043466625001231

https://youtu.be/VNDdoPhBWLA?si=gfX16WTyifgg0SSa
Unaufgeregtes Video. Kein Impfen tötet oder rettet.
Laaang aber ganz gut. Ich habe mitgenommen das verschmolzen Zellen sich nicht mehr vermehren. Beim Myelom evtl. eine gute News. Aber sie werden halt viel Zeugs produzieren können wie evtl. so hochleistungsfähige Getreidesorten. Kommt jetzt nicht so direkt vor war halt in meinem Kopf.

Zombiezellen also doch ein verzögertes Walking Dead?

https://en.m.wikipedia.org/wiki/Oroxylin_A
Das wurde erwähnt und Melatonin. Apherese ist nicht so meins. Klar unter starken Leidensdruck. Ist aber wie mit Zahnimplantaten, darf man wohl selber bezahlen. ACE2 Täuschkorper gibt es ja und vielleicht ist auch Glukosamin und co ein Täuschkorper.

Was blockiert die Furinspalte?

Red blood cell rupture, not clotting, drives vessel blockage in COVID-19, study finds
https://medicalxpress.com/news/2025-06-r...x9i6dKUzB6IEqeA

Zitat von Speedy im Beitrag #543

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Red blood cell rupture, not clotting, drives vessel blockage in COVID-19, study finds
https://medicalxpress.com/news/2025-06-r...x9i6dKUzB6IEqeA

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Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection
https://www.tandfonline.com/doi/full/10....27.2025.2514232

Understanding Neuroinflammation in Post-COVID-19 Syndrome: Biological Mechanisms, Diagnostic Biomarkers, and Therapeutic Prospects
https://www.preprints.org/manuscript/202506.1469/v1

Neuroimmune pathophysiology of long COVID
https://onlinelibrary.wiley.com/doi/10.1111/pcn.13855

Zitat von Speedy im Beitrag #547

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Neuroimmune pathophysiology of long COVID
https://onlinelibrary.wiley.com/doi/10.1111/pcn.13855

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The SARS-CoV-2 nucleocapsid protein induces microglia senescence- mediated cognitive impairment via glycolysis
https://www.researchsquare.com/article/rs-6872703/v1


2-Deoxy-D-glucose als Glycolysis Inhibitor würde mit einfallen unter anderem. Ansonsten auch Quercetin.